High Albumin Levels

Human serum albumin is that serum albumin present in human blood. It is usually the most plentiful protein in the blood plasma of humans; constituting around half the protein serum. The liver produces this serum. It is monomeric and soluble. The liver synthesizes albumin like preproalbumin, with the N-terminal peptide, which is removed prior to the releasing of nascent proteins from the coarse endoplasmic reticulum.

Blood has blood proteins, which aid in the proper body functioning. Varied types of serum proteins available in blood help in the maximum working of the immune structure. Serum globulin and serum albumin are the most crucial ones. The two proteins are produced by the liver.

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Functions of Albumin

 In the body, albumin has the following functions:

  • Maintaining oncotic pressure
  • Transporting thyroid hormones
  • Transporting the fat soluble proteins
  • Transporting fatty acids to liver
  • Transporting most drugs
  • Binding calcium ions
  • Preventing the photodegradation of folic acid

 

Albumin is responsible for preventing blood leaking inside the blood vessels. Albumin also facilitates the growth of tissues as well as fastens the healing process of tissue injuries. The testing of albumin is done in the kidney and liver diseases. The normal level range of albumin is between 3.4 and 5.4 g/dl.

 

High albumin levels – causes and signs

The medical term that is used in describing the high levels of serum albumin is hyperalbuminemia. Some of the major factors that lead to an elevated level of albumin in blood include:

  • Congestive cardiac failure
  • Tuberculosis
  • Severe infections
  • Severe dehydration
  • Congenital disorders
  • Malnourishment
  • Hepatitis
  • Chronic inflammatory disorders
  • Cancer
  • HIV
  • Kidney diseases
  • Overdosing cortisone drugs

The above mentioned disorders usually impair the human immune system, and thus elevate the protein levels in the body.

  High albumin levels in blood are normally a sign of a certain dysfunction inside the body. Based on the cause of this condition, like the kidney and liver diseases, the person will portray some clinical aspects.

 

Preparing For Serum Albumin Test

 Some medicines like the growth hormones, insulin and anabolic steroids can have an effect on this test. It is vital to tell the physician of any medications you are taking. The doctor will then advise you to alter the dosage of the medicine or even stop taking it before the examination is done.  You must not make any alterations to the dosage or medication unless instructed by the doctor.

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Serum Albumin Test and Results Interpretation  

The laboratory technician takes a blood sample in the arm for the test. Firstly, some antiseptic swipe or alcohol swab is used in cleaning the skin. Later, the upper part of the arm is tied using a band for the veins to swell with blood. This aids in finding the vein more simply. After the vein is identified, the technician will insert a needle attached to the vial and draw blood. One or several vials may be filled. The blood sample collected will then be sent to the laboratory for more analysis.

 The serum albumin test is usually a part of several other tests to check for kidney and liver functionality. The doctor will probably check all the results from the test that lead to the symptoms and later make some accurate diagnosis. When the albumin levels are low, several health conditions will be indicated, like:

  • Celiac disease
  • Crohn’s disease
  • Inflammation
  • Malnutrition
  • Liver disease
  • Shock
  • Nephrotic syndrome or nephritic syndrome

If the physician believes that the low serum is as a result of liver disease, they will order for other tests to establish the particular kind of liver disorder you are suffering. Some kinds of liver diseases include hepatocellular necrosis, cirrhosis and hepatitis.

When one has high levels of serum albumin, it means that they are either dehydrates or consume lots of proteins in their diet.  It is vital to know that the results can change based on the laboratory which analyzed the blood sample. Meeting with your doctor is paramount as it will shed more light on the test results.

 

Risk Factors of  Serum Albumin Test

 The serum albumin tests do not need large blood samples, so it is deemed a low risk process. Nonetheless, if it is hard for the technician to get your vein, you may experience some bruising and discomfort after and during the drawing of the blood sample.

It is important to tell the physician beforehand if there is any medical condition that can increase the chances of excess bleeding. Let the doctor aware whether you are consuming specific medications like blood thinners, which can lead to bleeding more than anticipated in the course of the procedure. Some of the side effects linked to serum albumin tests include:

  • Infections at the puncture area
  • Bruising or bleeding at the place where the needle is injected
  • Fainting upon seeing blood
  • Blood accumulation under the skin of the patient.

 

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